Question

A 36-year-old woman presents with chronic inflammatory polyarthritis affecting her hands and wrists for 6 months, early morning stiffness longer than 1 hour and elevated inflammatory markers. Rheumatoid factor and anti-CCP antibodies are positive. According to rheumatology guidelines, what is the most appropriate initial disease-modifying strategy?

Accepted Answer

Refer for early initiation of methotrexate-based DMARD therapy

Answer

Start paracetamol alone for symptomatic relief

Answer

Start non-steroidal anti-inflammatory drugs only

Answer

Delay DMARDs until radiological erosions occur

Answer

Use long-term corticosteroids alone as disease-modifying treatment

Practice question