A 70-year-old man with type 2 diabetes, CKD stage 3 (eGFR 45 mL/min/1.73 m²) and albuminuria is already on maximally tolerated ACE inhibitor and metfo...

Question

A 70-year-old man with type 2 diabetes, CKD stage 3 (eGFR 45 mL/min/1.73 m²) and albuminuria is already on maximally tolerated ACE inhibitor and metformin. His HbA1c is 58 mmol/mol. According to contemporary guidelines, which additional glucose-lowering agent provides proven renal and cardiovascular benefit in this setting?

Accepted Answer

An SGLT2 inhibitor such as empagliflozin

Answer

A DPP-4 inhibitor such as sitagliptin

Answer

A thiazolidinedione such as pioglitazone

Answer

A sulfonylurea such as gliclazide

Answer

Basal human insulin

au-amc MCQ (SBA): Type 2 diabetes with chronic kidney disease