A 48-year-old woman presents with progressive fatigue, pruritus, and jaundice. Laboratory tests show elevated alkaline phosphatase and GGT, mildly ele...

Question

A 48-year-old woman presents with progressive fatigue, pruritus, and jaundice. Laboratory tests show elevated alkaline phosphatase and GGT, mildly elevated ALT/AST, and positive antimitochondrial antibodies. Ultrasound shows no biliary obstruction. What is the most likely diagnosis?

Accepted Answer

Primary biliary cholangitis

Answer

Primary sclerosing cholangitis

Answer

Autoimmune hepatitis

Answer

Gallstone disease

Answer

Alcoholic hepatitis

ca-mccqe1 MCQ (SBA): Primary biliary cholangitis - diagnosis

A 48-year-old woman presents with progressive fatigue, pruritus, and jaundice. Laboratory tests show elevated alkaline phosphatase and GGT, mildly elevated ALT/AST, and positive antimitochondrial antibodies. Ultrasound shows no biliary obstruction. What is the most likely diagnosis?