A 68-year-old woman is taking an ACE inhibitor and a thiazide diuretic for hypertension and starts regular NSAIDs for osteoarthritis. She presents wit...

Question

A 68-year-old woman is taking an ACE inhibitor and a thiazide diuretic for hypertension and starts regular NSAIDs for osteoarthritis. She presents with fatigue and reduced urine output. Blood tests show rising creatinine and hyperkalaemia. What is the most likely mechanism of her acute kidney injury?

Accepted Answer

Haemodynamic compromise from the combination of ACE inhibitor, diuretic and NSAID

Answer

Prerenal azotaemia due to vomiting

Answer

Post-renal obstruction

Answer

Drug-induced haemolytic uraemic syndrome

Answer

Primary glomerulonephritis

au-amc MCQ (SBA): Drug-induced acute kidney injury