A 42-year-old woman presents with fatigue, weight loss, postural dizziness and hyperpigmentation of the palmar creases. Her sodium is 128 mmol/L and p...

Question

A 42-year-old woman presents with fatigue, weight loss, postural dizziness and hyperpigmentation of the palmar creases. Her sodium is 128 mmol/L and potassium 5.8 mmol/L. Morning serum cortisol is borderline low. Which investigation is most appropriate to confirm the suspected diagnosis?

Accepted Answer

Short Synacthen (ACTH stimulation) test

Answer

24-hour urinary free cortisol collection

Answer

Random serum ACTH level alone

Answer

MRI of the pituitary gland

Answer

Serum aldosterone-renin ratio

au-amc MCQ (SBA): Primary adrenal insufficiency

A 42-year-old woman presents with fatigue, weight loss, postural dizziness and hyperpigmentation of the palmar creases. Her sodium is 128 mmol/L and potassium 5.8 mmol/L. Morning serum cortisol is borderline low. Which investigation is most appropriate to confirm the suspected diagnosis?