A 25-year-old woman of Afro-Caribbean descent presents with malar rash, photosensitivity, arthralgia, and positive ANA and anti-dsDNA. Urinalysis show...

Question

A 25-year-old woman of Afro-Caribbean descent presents with malar rash, photosensitivity, arthralgia, and positive ANA and anti-dsDNA. Urinalysis shows proteinuria 1 g/day. What is the most appropriate initial management?

Accepted Answer

Hydroxychloroquine plus consider systemic corticosteroids and nephrology referral

Answer

High-dose NSAIDs only

Answer

Topical steroids only for the rash

Answer

No treatment until renal biopsy is done

Answer

Methotrexate monotherapy

ca-mccqe1 MCQ (SBA): Systemic lupus erythematosus with renal involvement

A 25-year-old woman of Afro-Caribbean descent presents with malar rash, photosensitivity, arthralgia, and positive ANA and anti-dsDNA. Urinalysis shows proteinuria 1 g/day. What is the most appropriate initial management?