A 65-year-old man with known coronary artery disease presents with 30 minutes of crushing central chest pain, diaphoresis, and nausea. ECG shows 3 mm ST elevation in leads II, III, and aVF with reciprocal ST depression in I and aVL. He presents to a rural hospital without PCI capability; the nearest PCI centre is 3 hours away by road. Symptoms began 90 minutes ago. What is the best reperfusion strategy?