A 74-year-old man on warfarin for atrial fibrillation presents with massive gastrointestinal haemorrhage and haemodynamic instability. His INR is 4.5....

Question

A 74-year-old man on warfarin for atrial fibrillation presents with massive gastrointestinal haemorrhage and haemodynamic instability. His INR is 4.5. According to best practice, what is the most appropriate reversal strategy?

Accepted Answer

Administer intravenous vitamin K and four-factor prothrombin complex concentrate

Answer

Stop warfarin only and observe

Answer

Administer vitamin K orally only

Answer

Administer fresh frozen plasma alone

Answer

Give platelet transfusion only

ca-mccqe1 MCQ (SBA): Warfarin-associated major bleeding

A 74-year-old man on warfarin for atrial fibrillation presents with massive gastrointestinal haemorrhage and haemodynamic instability. His INR is 4.5. According to best practice, what is the most appropriate reversal strategy?