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EasyPsychiatryMajor depressive disorderca-mccqe1ca-ccfp

A 45-year-old man presents with a 3-month history of low mood, anhedonia, poor sleep, and impaired concentration. He denies suicidal ideation. There is no history of mania or psychosis, and no substance misuse. According to CANMAT guidelines, what is an appropriate first-line treatment option for moderate major depressive disorder?

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