Question

A 35-year-old woman presents with recurrent painful oral ulcers and a 3-month history of fatigue. Examination reveals glossitis and angular cheilitis. Full blood count shows Hb 92 g/L, MCV 112 fL. What is the most appropriate initial investigation to determine the cause of her macrocytosis?

Accepted Answer

Serum vitamin B12 and folate levels

Answer

Serum ferritin

Answer

Reticulocyte count only

Answer

Bone marrow biopsy

Answer

Coagulation profile

Practice question

A 35-year-old woman presents with recurrent painful oral ulcers and a 3-month history of fatigue. Examination reveals glossitis and angular cheilitis. Full blood count shows Hb 92 g/L, MCV 112 fL. What is the most appropriate initial investigation to determine the cause of her macrocytosis?