MediumCardiologyStroke prevention in non-valvular atrial fibrillationau-amcau-racpau-racgp
A 78-year-old man with permanent non-valvular atrial fibrillation is reviewed in general practice. He has hypertension and type 2 diabetes mellitus but no history of stroke or major bleeding. His CHA₂DS₂-VA score is 4. Renal function is normal and echocardiogram shows no significant valvular disease. He is currently taking aspirin 100 mg daily. According to Australian atrial fibrillation guidelines, which is the most appropriate antithrombotic management?