Question

A 36-year-old woman presents with bilateral wrist and hand pain, morning stiffness >1 hour and swelling of MCP and PIP joints for 3 months. Rheumatoid factor and anti-CCP are positive. What is the most appropriate initial disease-modifying treatment?

Accepted Answer

Methotrexate as first-line DMARD

Answer

NSAIDs only

Answer

Oral corticosteroids long-term as monotherapy

Answer

Hydroxychloroquine plus sulfasalazine only

Answer

Biologic therapy as first-line

Practice question

A 36-year-old woman presents with bilateral wrist and hand pain, morning stiffness >1 hour and swelling of MCP and PIP joints for 3 months. Rheumatoid factor and anti-CCP are positive. What is the most appropriate initial disease-modifying treatment?