A 45-year-old man with depression treated with sertraline for 6 weeks shows partial response but remains significantly symptomatic. He has tolerated t...

Question

A 45-year-old man with depression treated with sertraline for 6 weeks shows partial response but remains significantly symptomatic. He has tolerated treatment well. According to CANMAT guidance, what is the most appropriate next step?

Accepted Answer

Increase sertraline dose if not yet at maximum tolerated

Answer

Stop sertraline and start another SSRI at low dose

Answer

Add a second antidepressant immediately

Answer

Stop medication and switch to psychotherapy alone

Answer

Declare treatment failure and refer for ECT

ca-mccqe1 MCQ (SBA): Optimising antidepressant therapy

A 45-year-old man with depression treated with sertraline for 6 weeks shows partial response but remains significantly symptomatic. He has tolerated treatment well. According to CANMAT guidance, what is the most appropriate next step?