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MediumNephrologyACE inhibitor use in CKDca-mccqe1ca-rcpsc-im

A 59-year-old man with chronic kidney disease stage 3, hypertension and diabetes is prescribed ramipril 10 mg daily. Two weeks later, serum creatinine rises from 110 µmol/L to 130 µmol/L and potassium increases from 4.5 to 5.1 mmol/L. He is asymptomatic, blood pressure is 128/76 mm Hg and there is no volume depletion. How should this change be managed?

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