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MediumPsychiatryMajor depressive disorderca-mccqe1ca-ccfpca-rcpsc-im

A 35-year-old woman presents with low mood, anhedonia, poor concentration, and early-morning awakening for 6 weeks. She has no psychotic symptoms or substance use and denies suicidal ideation. Function is impaired at work. According to CANMAT 2023 guidelines, which is the most appropriate first-line management?

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