Question

A 72-year-old woman on warfarin for atrial fibrillation presents with sudden onset headache and vomiting. CT brain shows a large intracerebral haemorrhage. INR is 3.5. According to Australian practice, what is the most appropriate immediate reversal strategy?

Accepted Answer

Administer intravenous vitamin K and prothrombin complex concentrate (PCC)

Answer

Cease warfarin and observe without further action

Answer

Administer vitamin K orally only

Answer

Administer fresh frozen plasma alone

Answer

Switch to a direct oral anticoagulant immediately

Practice question

A 72-year-old woman on warfarin for atrial fibrillation presents with sudden onset headache and vomiting. CT brain shows a large intracerebral haemorrhage. INR is 3.5. According to Australian practice, what is the most appropriate immediate reversal strategy?