Question

A 70-year-old man with long-standing hypertension and coronary artery disease presents with progressive breathlessness on exertion and ankle swelling. Echocardiography shows a left ventricular ejection fraction of 30% and global hypokinesis. According to contemporary heart failure guidelines, which combination best represents the recommended core disease-modifying pharmacological therapy for symptomatic heart failure with reduced ejection fraction?

Accepted Answer

ACE inhibitor (or ARNI), evidence-based beta blocker, mineralocorticoid receptor antagonist and SGLT2 inhibitor

Answer

ACE inhibitor plus beta blocker only

Answer

ACE inhibitor, beta blocker and loop diuretic

Answer

Angiotensin receptor blocker and loop diuretic only

Answer

Digoxin and loop diuretic only

Practice question