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EasyCardiologyAcute pulmonary oedemaau-acemau-amc

A 70-year-old man with known ischaemic cardiomyopathy presents to the emergency department with acute severe dyspnoea, orthopnoea and frothy pink sputum. He is tachypnoeic, hypertensive at 190/110 mmHg, with widespread crackles to the lung apices and oxygen saturation of 88% on room air. Which immediate intervention is most appropriate?

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