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MediumRheumatologyRheumatoid arthritisau-amcau-racp

A 46-year-old woman presents with painful swollen MCP and PIP joints of both hands for 4 months with morning stiffness lasting over an hour. ESR and CRP are elevated, and rheumatoid factor and anti-CCP are positive. X-rays show no erosions. What is the recommended initial disease-modifying treatment?

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