MediumNephrologyAcute kidney injury vs chronic kidney diseaseca-mccqe1ca-rcpsc-im
A 61-year-old woman with long-standing hypertension and diabetes presents with gradual onset fatigue, pruritus and oedema. Her creatinine is 260 µmol/L (baseline 100 µmol/L a year ago), eGFR 18 mL/min/1.73 m², and urinalysis shows heavy proteinuria. Which of the following features would most strongly support a diagnosis of acute kidney injury rather than chronic kidney disease?