A 48-year-old woman presents with fatigue, weight gain, constipation and feeling cold. Examination reveals dry skin and bradycardia. Thyroid function ...

Question

A 48-year-old woman presents with fatigue, weight gain, constipation and feeling cold. Examination reveals dry skin and bradycardia. Thyroid function tests show TSH 18 mIU/L (elevated) and free T4 7 pmol/L (reduced). She weighs 70 kg. What is the most appropriate initial thyroid hormone replacement regimen?

Accepted Answer

Start levothyroxine 75-100 micrograms once daily in the morning

Answer

Start liothyronine 25 micrograms twice daily

Answer

Start levothyroxine 300 micrograms once daily

Answer

Start desiccated thyroid extract

Answer

No treatment is required; repeat thyroid function in 6 months

au-racgp MCQ (SBA): Primary hypothyroidism