A 45-year-old man presents with a 3-month history of epigastric pain relieved by food and antacids. He takes ibuprofen intermittently for back pain. Endoscopy shows a duodenal ulcer and biopsy is positive for Helicobacter pylori. He has no macrolide allergy. According to the Toronto Consensus, which regimen is an appropriate first-line H. pylori eradication therapy in Canada?