Question

A 19-year-old woman with type 1 diabetes presents with nausea, abdominal pain and polyuria. Capillary glucose is 26 mmol/L, venous pH 7.18, bicarbonate 10 mmol/L, and serum ketones are elevated. She is haemodynamically stable. According to Diabetes Canada guidance, which insulin regimen is recommended initially for treatment of diabetic ketoacidosis (DKA) in adults?

Accepted Answer

Intravenous regular insulin infusion 0.10 units/kg/h without initial bolus

Answer

Intravenous regular insulin bolus 0.1 units/kg then infusion 0.05 units/kg/h

Answer

Continuous subcutaneous rapid-acting insulin via insulin pump at double her basal rate

Answer

Intravenous regular insulin infusion 0.01 units/kg/h to avoid cerebral oedema

Answer

Twice-daily premixed insulin subcutaneously with IV fluids

Practice question