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MediumRespiratoryStable COPD managementau-amcau-racp

A 70-year-old man with COPD (FEV1 42% predicted) reports daily symptoms and has had two exacerbations requiring oral corticosteroids and antibiotics in the past year despite using a long-acting muscarinic antagonist (LAMA) inhaler regularly. He is an ex-smoker. What is the most appropriate adjustment to his maintenance inhaled therapy?

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