MediumRespiratoryAcute exacerbation of COPDau-amcau-racgp
A 68-year-old man with known chronic obstructive pulmonary disease (COPD) presents with an increase in breathlessness, a change in sputum to yellow-green and increased sputum volume over 3 days. He has no radiographic consolidation and remains haemodynamically stable. According to COPD-X guidelines, what is the main indication for starting antibiotics in an acute COPD exacerbation?