A 27-year-old man with a history of intravenous drug use presents with fever and a new systolic murmur. Blood cultures grow methicillin-sensitive Stap...

Question

A 27-year-old man with a history of intravenous drug use presents with fever and a new systolic murmur. Blood cultures grow methicillin-sensitive Staphylococcus aureus. Transoesophageal echocardiography shows a 1.5 cm vegetation on the tricuspid valve. What is the MOST appropriate initial management?

Accepted Answer

Intravenous cloxacillin or cefazolin

Answer

Oral amoxicillin-clavulanate

Answer

Oral doxycycline

Answer

No antibiotics until repeat cultures are obtained

Answer

Immediate valve replacement without antibiotics

ca-mccqe1 MCQ (SBA): Infective endocarditis - MSSA