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EasyPsychiatryRecurrent major depressive disorder - antidepressant choiceau-racgpau-amc

A 45-year-old man presents with 3 months of low mood, anhedonia and hopelessness. He has had two previous depressive episodes that responded well to sertraline. He now has passive suicidal ideation but no active plan, and no bipolar features. He is agreeable to medication. Which antidepressant is the most appropriate first choice?

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