A 54-year-old man is newly diagnosed with type 2 diabetes after fasting plasma glucose 8.5 mmol/L on two occasions and HbA1c 7.5%. He is overweight bu...

Question

A 54-year-old man is newly diagnosed with type 2 diabetes after fasting plasma glucose 8.5 mmol/L on two occasions and HbA1c 7.5%. He is overweight but otherwise healthy, with normal renal function and no cardiovascular disease. What is the most appropriate initial pharmacologic management?

Accepted Answer

Start metformin in addition to lifestyle changes

Answer

Lifestyle modification only for 12 months before considering medication

Answer

Start basal-bolus insulin therapy immediately

Answer

Start a sulfonylurea as first-line monotherapy

Answer

Start a GLP-1 receptor agonist as first-line monotherapy

ca-mccqe1 MCQ (SBA): Type 2 diabetes initial therapy

A 54-year-old man is newly diagnosed with type 2 diabetes after fasting plasma glucose 8.5 mmol/L on two occasions and HbA1c 7.5%. He is overweight but otherwise healthy, with normal renal function and no cardiovascular disease. What is the most appropriate initial pharmacologic management?