A 50-year-old man presents with fever, night sweats and weight loss over 3 months. Examination reveals painless cervical lymphadenopathy and splenomeg...

Question

A 50-year-old man presents with fever, night sweats and weight loss over 3 months. Examination reveals painless cervical lymphadenopathy and splenomegaly. FBC shows normocytic anaemia and lymphocytosis. Which is the most appropriate initial investigation to establish a definitive diagnosis?

Accepted Answer

Excisional lymph node biopsy

Answer

Peripheral blood film only

Answer

Fine-needle aspiration of a lymph node

Answer

Bone marrow biopsy only

Answer

CT scan of neck, chest, abdomen and pelvis

au-amc MCQ (SBA): Lymphoma diagnosis

A 50-year-old man presents with fever, night sweats and weight loss over 3 months. Examination reveals painless cervical lymphadenopathy and splenomegaly. FBC shows normocytic anaemia and lymphocytosis. Which is the most appropriate initial investigation to establish a definitive diagnosis?