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MediumGastroenterologyPrimary biliary cholangitisau-amcau-racp

A 54‑year‑old woman presents with fatigue, pruritus and jaundice. Laboratory tests show elevated alkaline phosphatase and gamma‑GT with mildly raised transaminases. Ultrasound shows no biliary obstruction. Anti‑mitochondrial antibody is positive at high titre. What is the most likely diagnosis?

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