A 72-year-old man presents with melaena and light-headedness. He is on low-dose aspirin for secondary prevention of myocardial infarction and has a hi...

Question

A 72-year-old man presents with melaena and light-headedness. He is on low-dose aspirin for secondary prevention of myocardial infarction and has a history of osteoarthritis treated with regular ibuprofen. His BP is 90/60 mmHg and pulse 110 bpm. After resuscitation and endoscopic therapy for a bleeding duodenal ulcer, which change to his medications is most appropriate to reduce rebleeding risk while maintaining cardiovascular protection?

Accepted Answer

Cease ibuprofen, recommence aspirin within a few days and start a proton pump inhibitor

Answer

Stop both aspirin and ibuprofen permanently

Answer

Continue both aspirin and ibuprofen unchanged

Answer

Switch aspirin to clopidogrel and continue ibuprofen

Answer

Add a COX-2 inhibitor and continue both aspirin and ibuprofen

au-amc MCQ (SBA): Peptic ulcer bleeding on antiplatelets