A 63-year-old man with chronic knee pain due to osteoarthritis has been taking over-the-counter ibuprofen regularly and now has an eGFR of 45 mL/min/1...

Question

A 63-year-old man with chronic knee pain due to osteoarthritis has been taking over-the-counter ibuprofen regularly and now has an eGFR of 45 mL/min/1.73 m². According to CKD and analgesia guidance, which is the most appropriate advice regarding ongoing pain management?

Accepted Answer

Avoid regular NSAIDs and consider alternatives such as paracetamol, topical agents, exercise and referral for non-pharmacological therapies

Answer

Continue NSAIDs indefinitely as they have no impact on kidney function

Answer

Increase NSAID dose to improve pain control despite CKD

Answer

Use strong opioids as first-line replacement for NSAIDs

Answer

Cease all analgesia to protect kidney function

au-amc MCQ (SBA): Analgesia in chronic kidney disease

A 63-year-old man with chronic knee pain due to osteoarthritis has been taking over-the-counter ibuprofen regularly and now has an eGFR of 45 mL/min/1.73 m². According to CKD and analgesia guidance, which is the most appropriate advice regarding ongoing pain management?