Question

A 54-year-old woman presents with chronic diarrhoea and abdominal pain. Colonoscopy and biopsy confirm ulcerative colitis limited to the rectum and sigmoid colon. What is the most appropriate initial treatment?

Accepted Answer

Topical rectal mesalazine (suppositories or enemas)

Answer

Oral mesalazine only

Answer

Systemic corticosteroids only

Answer

Thiopurines as first-line

Answer

Biologic therapy as first-line

Practice question

A 54-year-old woman presents with chronic diarrhoea and abdominal pain. Colonoscopy and biopsy confirm ulcerative colitis limited to the rectum and sigmoid colon. What is the most appropriate initial treatment?