Question

A 32-year-old woman presents with a 3-month history of diarrhoea, bloating and weight loss. She has iron deficiency anaemia (Hb 100 g/L, ferritin 8 µg/L). You suspect coeliac disease. What is the most appropriate initial diagnostic test?

Accepted Answer

Serum tissue transglutaminase IgA and total IgA

Answer

Duodenal biopsy without further tests

Answer

HLA DQ2/DQ8 typing

Answer

Empirical gluten-free diet for 3 months

Answer

Faecal calprotectin

Practice question

A 32-year-old woman presents with a 3-month history of diarrhoea, bloating and weight loss. She has iron deficiency anaemia (Hb 100 g/L, ferritin 8 µg/L). You suspect coeliac disease. What is the most appropriate initial diagnostic test?