Question

A 52-year-old woman with chronic reflux symptoms requires proton pump inhibitor (PPI) therapy to control her GORD. She has been taking high-dose esomeprazole for 2 years with good relief. According to Australian guidance on PPI stewardship, what is the most appropriate next step?

Accepted Answer

Step down to the lowest effective PPI dose and consider intermittent therapy

Answer

Continue high-dose PPI indefinitely without review

Answer

Cease PPI abruptly and switch to antacids only

Answer

Switch to H2 receptor antagonist as first-line long-term therapy

Answer

Start long-term dual therapy with PPI and prokinetic agent

Practice question

A 52-year-old woman with chronic reflux symptoms requires proton pump inhibitor (PPI) therapy to control her GORD. She has been taking high-dose esomeprazole for 2 years with good relief. According to Australian guidance on PPI stewardship, what is the most appropriate next step?