Question

A 72-year-old woman with non-valvular atrial fibrillation, hypertension and type 2 diabetes mellitus is reviewed in clinic. She has no prior stroke or TIA. Her CHA₂DS₂-VASc score is 4. Renal and liver function are normal. Which is the most appropriate stroke prevention strategy?

Accepted Answer

Direct oral anticoagulant (DOAC) at stroke-prevention dose

Answer

No antithrombotic therapy because her bleeding risk is high at her age

Answer

Aspirin 100 mg daily as sole antithrombotic therapy

Answer

Warfarin with a target INR of 1.5-2.0

Answer

Dual antiplatelet therapy with aspirin and clopidogrel

Practice question

A 72-year-old woman with non-valvular atrial fibrillation, hypertension and type 2 diabetes mellitus is reviewed in clinic. She has no prior stroke or TIA. Her CHA₂DS₂-VASc score is 4. Renal and liver function are normal. Which is the most appropriate stroke prevention strategy?