Question

A 28-year-old man presents with a painless genital ulcer and generalised non-tender lymphadenopathy. He recently had unprotected intercourse with a new partner. Which is the most appropriate initial investigation?

Accepted Answer

Dark-field microscopy of ulcer exudate or treponemal PCR, plus syphilis serology

Answer

HIV serology only

Answer

Urine nucleic acid test for Chlamydia only

Answer

HSV PCR only

Answer

Empirical benzathine penicillin without testing

Practice question

A 28-year-old man presents with a painless genital ulcer and generalised non-tender lymphadenopathy. He recently had unprotected intercourse with a new partner. Which is the most appropriate initial investigation?