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MediumRespiratoryCOPD exacerbation - oxygen and bronchodilator strategyau-amcau-acemau-racp

A 65-year-old man with known COPD (FEV₁ 45% predicted) presents with increased dyspnoea, sputum volume and purulence over 3 days. He is afebrile and saturating 92% in air. Which of the following treatments is most appropriate as part of initial management of this moderate COPD exacerbation in the emergency department?

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