Question

A 47-year-old man presents with intermittent abdominal pain and diarrhoea with blood and mucus for 3 months. Colonoscopy confirms left-sided ulcerative colitis with moderate activity. Which is the most appropriate first-line induction therapy?

Accepted Answer

Combined oral and rectal mesalazine

Answer

Oral mesalazine alone

Answer

Topical rectal steroids alone

Answer

Systemic prednisolone alone

Answer

Biologic therapy with anti-TNF agent as first-line

Practice question

A 47-year-old man presents with intermittent abdominal pain and diarrhoea with blood and mucus for 3 months. Colonoscopy confirms left-sided ulcerative colitis with moderate activity. Which is the most appropriate first-line induction therapy?