MediumCardiologyHeart failure with reduced ejection fractionau-amcau-racp
A 68-year-year-old man with a history of ischaemic cardiomyopathy (left ventricular ejection fraction 30%) presents to his GP for routine review. He is mildly breathless on climbing one flight of stairs. Current medications are frusemide 40 mg daily and perindopril 2 mg daily. Blood pressure is 120/70 mmHg and renal function is normal. Which of the following drug classes has the strongest evidence for improving survival and should be optimised in all suitable patients with heart failure with reduced ejection fraction?