Question

A 70-year-old with severe CAP is stable after 72 hours. Sputum culture grows Streptococcus pneumoniae susceptible to penicillin. What de-escalation is appropriate?

Accepted Answer

Switch to targeted narrow β-lactam (e.g., IV penicillin/ampicillin)

Answer

Continue broad anti-pseudomonal therapy

Answer

Add vancomycin

Answer

Stop antibiotics immediately

Answer

Change to macrolide monotherapy

Practice question

A 70-year-old with severe CAP is stable after 72 hours. Sputum culture grows Streptococcus pneumoniae susceptible to penicillin. What de-escalation is appropriate?