A 63-year-old with severe CAP is improving. MRSA nares PCR was positive, but blood/sputum cultures remain negative at 48 hours, and clinical risk is l...

Question

A 63-year-old with severe CAP is improving. MRSA nares PCR was positive, but blood/sputum cultures remain negative at 48 hours, and clinical risk is low. What is recommended?

Accepted Answer

De-escalate and stop MRSA coverage

Answer

Continue MRSA coverage indefinitely

Answer

Switch to linezolid now

Answer

Add vancomycin plus piperacillin-tazobactam

Answer

Obtain bronchoscopy to justify stopping therapy

us-abim MCQ (SBA): CAP De-escalation

A 63-year-old with severe CAP is improving. MRSA nares PCR was positive, but blood/sputum cultures remain negative at 48 hours, and clinical risk is low. What is recommended?