Question

A 54-year-old with severe watery diarrhea after recent antibiotics tests positive for C. difficile. First episode, nonfulminant. Optimal initial therapy?

Accepted Answer

Fidaxomicin 200 mg PO twice daily for 10 days

Answer

Metronidazole 500 mg PO TID for 10 days

Answer

Vancomycin 125 mg PO QID for 10 days

Answer

Rifaximin 550 mg PO TID for 14 days

Answer

Probiotics alone

Practice question

A 54-year-old with severe watery diarrhea after recent antibiotics tests positive for C. difficile. First episode, nonfulminant. Optimal initial therapy?