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ModerateRespiratory MedicineCOPD Exacerbation (NIV)us-abemus-abimus-usmle-step-2

A 59-year-old with COPD presents with acute exacerbation and hypercapnia. pH 7.28, PaCO₂ 64 mm Hg, RR 30, using accessory muscles, persistent hypoxia on supplemental O₂. Best next step?

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