A 66-year-old man with atrial fibrillation and a prior transient ischemic attack is on warfarin with unstable INRs. He prefers a direct oral anticoagu...

Question

A 66-year-old man with atrial fibrillation and a prior transient ischemic attack is on warfarin with unstable INRs. He prefers a direct oral anticoagulant (DOAC) and has an estimated glomerular filtration rate (eGFR) of 48 mL/min/1.73m², and a weight of 85 kg. What is the best option?

Accepted Answer

Switch to apixaban with renal-appropriate dosing

Answer

Continue warfarin despite INR lability

Answer

Switch to dabigatran; avoid in CKD

Answer

Use aspirin only

Answer

Use rivaroxaban plus aspirin

us-abim MCQ (SBA): Switching to DOAC

A 66-year-old man with atrial fibrillation and a prior transient ischemic attack is on warfarin with unstable INRs. He prefers a direct oral anticoagulant (DOAC) and has an estimated glomerular filtration rate (eGFR) of 48 mL/min/1.73m², and a weight of 85 kg. What is the best option?