A 64-year-old hospitalized for pneumonia has a rising creatinine after vancomycin + piperacillin-tazobactam. Which stewardship step is best when cultu...

Question

A 64-year-old hospitalized for pneumonia has a rising creatinine after vancomycin + piperacillin-tazobactam. Which stewardship step is best when cultures show S. pneumoniae susceptible to ceftriaxone?

Accepted Answer

Stop piperacillin-tazobactam and continue vancomycin

Answer

Continue broad-spectrum therapy for 7 days

Answer

De-escalate to ceftriaxone monotherapy

Answer

Switch to linezolid

Answer

Add aminoglycoside

us-abim MCQ (SBA): Antibiotic De-escalation

A 64-year-old hospitalized for pneumonia has a rising creatinine after vancomycin + piperacillin-tazobactam. Which stewardship step is best when cultures show S. pneumoniae susceptible to ceftriaxone?