Question

A 58-year-old with ulcerative colitis flare has C. difficile infection confirmed. It is his first episode, non-fulminant. Best initial therapy?

Accepted Answer

Fidaxomicin 200 mg PO twice daily for 10 days

Answer

Metronidazole 500 mg PO three times daily for 10-14 days

Answer

Bezlotoxumab alone

Answer

Vancomycin 125 mg PO four times daily for 10 days is preferred over fidaxomicin

Answer

Probiotics alone

Practice question

A 58-year-old with ulcerative colitis flare has C. difficile infection confirmed. It is his first episode, non-fulminant. Best initial therapy?