A 70-year-old with COPD has persistent dyspnea and two moderate exacerbations last year despite LAMA monotherapy. Eosinophils 180/µL. Best next pharma...

Question

A 70-year-old with COPD has persistent dyspnea and two moderate exacerbations last year despite LAMA monotherapy. Eosinophils 180/µL. Best next pharmacologic step?

Accepted Answer

Add LABA to create dual bronchodilation (LABA/LAMA)

Answer

Add inhaled corticosteroid to form triple therapy (ICS/LABA/LAMA)

Answer

Switch to ICS/LABA

Answer

Start chronic oral prednisone 5 mg daily

Answer

Add theophylline

us-abim MCQ (SBA): COPD-Pharmacologic Escalation

A 70-year-old with COPD has persistent dyspnea and two moderate exacerbations last year despite LAMA monotherapy. Eosinophils 180/µL. Best next pharmacologic step?