Question

A 76-year-old woman with atrial fibrillation and a history of stroke is on warfarin with a time in therapeutic range (TTR) of 40%. Her creatinine clearance is 55 mL/min. What is the best strategy?

Accepted Answer

Switch to a direct oral anticoagulant (DOAC) if no contraindication

Answer

Continue warfarin unchanged

Answer

Add aspirin to warfarin

Answer

Stop anticoagulation

Answer

Switch to low-dose warfarin (INR 1.5-2.0)

Practice question

A 76-year-old woman with atrial fibrillation and a history of stroke is on warfarin with a time in therapeutic range (TTR) of 40%. Her creatinine clearance is 55 mL/min. What is the best strategy?