Question

A 58-year-old with nonsevere first episode C. difficile infection (WBC 11,000/µL; Cr 1.1 mg/dL) asks about therapy. Best initial treatment?

Accepted Answer

Fidaxomicin 200 mg twice daily for 10 days

Answer

Metronidazole 500 mg TID for 10 days

Answer

Oral vancomycin 125 mg QID for 10 days is preferred over fidaxomicin

Answer

Stop antibiotics only; no specific CDI therapy

Answer

Probiotics as monotherapy

Practice question

A 58-year-old with nonsevere first episode C. difficile infection (WBC 11,000/µL; Cr 1.1 mg/dL) asks about therapy. Best initial treatment?